KEGG   Mus musculus (house mouse): 108147
Entry
108147            CDS       T01002                                 
Symbol
Atic, 2610509C24Rik
Name
(RefSeq) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00230  Purine metabolism
mmu00670  One carbon pool by folate
mmu01100  Metabolic pathways
mmu01523  Antifolate resistance
Module
mmu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    108147 (Atic)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    108147 (Atic)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    108147 (Atic)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    108147 (Atic)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     108147 (Atic)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     108147 (Atic)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   108147 (Atic)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS
Other DBs
NCBI-GeneID: 108147
NCBI-ProteinID: NP_080471
MGI: 1351352
Ensembl: ENSMUSG00000026192
UniProt: Q9CWJ9
Position
1:71596315..71618562
AA seq 592 aa
MAPSQLALFSVSDKTGLVEFARSLASLGLSLVASGGTAKAIRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDAADMARLDFNLVRVVVCNLYPFVKTVASPDVTVEAA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYAGVAAEMHGSDSKDTSLETRRHLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVTELRGAVDIPAAASFKHVSPAGAAVGVPLSEDEARVCMVYDLYPTLTPLA
VAYARARGADRMSSFGDFVALSDICDVPTAKIISREVSDGIVAPGYEEEALKILSKKKNG
NYCVLQMDQSYKPDENEVRTLFGLRLSQKRNNGVVDKSLFSNIVTKNKDLPESALRDLIV
ATVAVKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKA
GVKRAEISNAIDQYVTGTIGEGEDLVKWEALFEEVPELLTEAEKKEWVDKLSGVSVSSDA
FFPFRDNVDRAKRSGVAYIVAPSGSTADKVVIEACDELGIVLAHTDLRLFHH
NT seq 1779 nt   +upstreamnt  +downstreamnt
atggctccgtctcagcttgccctgttcagtgtgtctgacaaaactggcctcgtggaattt
gccagaagtctcgcgtctcttggtttgagtctggtcgcttccggaggcacggcaaaagcg
atcagggatgctggcctggcagtcagagatgtgtctgagctaacagggttccctgaaatg
ttagggggacgcgtgaaaaccttgcaccctgcggtccatgctgggatcttggcacgcaac
attccagaagacgctgcagacatggccaggcttgatttcaaccttgtaagggttgtggtc
tgtaacctgtaccccttcgtgaagactgtggcttctccagatgtaactgttgaggcagct
gttgaacaaattgatattggtggcgtgacattactgagagctgcagccaaaaaccacgct
cgagtgacagtcgtctgtgaaccagaggactatgcgggggtagctgcagagatgcacggc
tctgatagtaaggacacctccctagagaccaggcgccacttggccttgaaggcattcact
cataccgctcaatacgatgaagcaatttcagattacttcaggaaacagtacagtaaggga
atttctcagatgcccttgcggtatgggatgaacccccatcagactcctgcccagttgtat
acgctgaagcccaaacttcccatcacagttctcaatggagccccaggattcataaacttg
tgtgacgctttgaacgcctggcagctggtgacagagctgagaggagcagtagacatccca
gcggctgcttctttcaagcacgtcagcccggcaggtgctgctgttggggttccactcagt
gaggacgaggccagagtctgcatggtctatgacctctacccgaccctcacgcccctggcc
gttgcatatgcaagagcaagaggagctgataggatgtcttcatttggtgattttgttgca
ttgtctgacatttgtgatgtcccaactgcaaaaattatctccagagaagtgtcggatggt
attgttgccccgggatatgaagaagaagccttgaaaatactttctaaaaagaaaaatgga
aactactgtgttcttcagatggaccagtcctacaaaccagatgaaaatgaagttcgaaca
ctctttggtcttcgtttaagccagaagagaaataatggtgtcgttgacaagtcattattt
agcaatattgtcaccaagaataaagatctgccggagtctgcactcagagacctcattgtc
gccaccgtcgctgtcaagtatactcagtctaattcggtgtgctatgccaaggatgggcag
gttattggcatcggagcaggacagcagtctcggatacactgcactcgccttgcaggtgat
aaggcaaactcttggtggcttcggcaccacccacgagtgctgtccatgaagtttaaagcc
ggggtgaagagagcagagatctccaatgcgattgatcagtatgtgaccggcactatcggt
gagggcgaagacctggtgaaatgggaagcactgttcgaagaggttcctgagttactcacg
gaggcggagaagaaggaatgggtggacaagctgagcggcgtgtctgtcagctccgacgcc
ttctttcctttcagggataatgtggaccgagctaaaaggagtggtgtggcctacattgtc
gctccatctggatctactgctgacaaggttgtgattgaggcgtgcgacgagctggggatt
gtcttggctcatacggatctccggctcttccaccactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (33)   
   RefSeq(nuc) (1)   
   GenBank (16)   
   EMBL (16)   
Protein domain (2)   
   Pfam (2)   
All databases (65)   

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